This is of interest to all researchers using GA Animals, such as Athymic nudes, NSGs and Db/DB mice among others, to fund out if you need a project authorisation or not when using them. Note that the EU has published another guide on the use and maintenance of genetically lateral animals. This flowchart provides a good synopsis though please read the August2023 regulatory update available on SharePoint LAPBRU USERS > REFERENCES-SOPS-3RS > EC GUIDES.