AMENDMENTS TO PROJECT AUTHORIZATION THAT REQUIRE THE COMPLIANCE OFFICER'S SIGNATURE

Changes to the application form which need to be referred back to the CO for signature:

1. Section A - Changes to proposed authorisation holder

2. Section B1 – Changes to project manager

3. Section B2 – Changes to deputy project manager

4. Section B3 – Addition of a collaborating establishment

5. Section B3 – Additional locations (other than the authorised user establishment)

6. Section C – Total number of animals per species to be used

7. Section C – Changes to individuals who will be performing procedures

8. Section F – Any changes whatsoever

9. Section G1 – Changes to the information under the Refinement heading only

10.       Section G3 – Any changes to information on animal species

Changes to the application form which do not need to be referred back to the CO for signature:

1. Section C – Project title

2. Section C – Regulatory requirements/production or diagnostic purposes/ethics committee questions

3. Section C – Duration of work

4. Section C – Estimated start date of work

5. Section D1 – Project details

6. Section D2 – Purpose of project

7. Section G1 – Replacement

8. Section G1 – Reduction

9. Section G2 – Animals to be used