Saturday, 5 December 2020

HPRA REGULATORY UPDATE- NOV20

Summary:

🎄 The HPRA will be closed for the Christmas Season from the 23rd of December to the 4th of January. 

💰There are no increases in the HPRA fees in general, though from now on, fees are payable per individual and per establishment.

👮The establishment can now provide a list of "inactive" individuals on HPRA's request. Information can be gathered by the establishments during the year and only facilitated when asked. Applications can subsequently be reactivated with non additional penalty associated to it. 


👮 There is a new template for the NTPS to facilitate a central, searchable EC-based database. All submissions from the 1-12-20 shall use this new template. No grace period is considered in this instance.

📚 PLEASE CHECK NEW UPDATES ON GUIDES AND APPLICATIONS!!!! The have been all updated.

📓Statistical returns for 2020 will use the same format used up until now, though it will change in 2021. A new form will be circulated soon so information is not lost from January 2021 onwards. The HPRA Regulatory Update explains more comprehensibly and in detail the new measures.

Please go to the main document there are several useful links in wide range of topics of interest!








Sunday, 20 September 2020

SUBSCRIBE TO THE 3 MINUTE 3RS PODCAST!!!





Every month, 3 minute 3Rs provide a recap of the latest 3Rs research papers, chosen by Lab Animal, the North American 3Rs Collaborative and the NC3Rs....subscribe ...why not?...3 minutes ....it is all it takes!

Wednesday, 5 August 2020

CRACK IT!

Up to £3.5 million funding is available to solve five Challenges identified jointly by the NC3Rs and Sponsors....and CRACK IT. For more information on the challenges: https://nc3rs.org.uk/news/crack-it-challenges-2020-announced

Wednesday, 15 July 2020

NC3Rs JUL20

New ARRIVE Guidelines, the ARRIVE guidelines have been revised and improved in ARRIVE 2.0 with a new website......if you do not want to read but being told then register in their webinar that takes place on Tuesday 18 August at 14:00.

This months issue of NC3Rs also includes  advice on how to embed the 3Rs in Covid-19 return to work practices, funding for training Fellowships and a webinar on Best Practice in Experimental design and much more.

Please visit the NC3Rs for more information...always time well spent!!!

Monday, 1 June 2020

MAY 2020- HPRA REGULATORY UPDATE


The HPRA has circulated a 9 page regulatory update. A copy is also available on the LAPBRU USERS folder,.... so no panic if you cannot find the attachment in the sea of e-mails! It contains information on on Covid-19 research, resources and their responses. They alert us on the new IA form, so no old form will be accepted after the 18th of July. Their guides have been updated as well.
There is a wealth of links on alternatives and refinements and advice on how to complete the refinement section of the PA application, key words to use and minimum links to check.
There is also a link to a paper regarding "research integrity in Universities". Though provoking????

Saturday, 23 May 2020

....OVER 80 PDF PRESENTATIONS!!!

Hi all,
Not sure if you can stand another webinar, online training, information link, free access to online courses....surely you are twiddling your thumbs and looking for something to do in the lockdown....NOT!!!!  ðŸ˜¤ Not need for 🤬 you are probably busier than pre-lockdown and you are not welcoming this. Take a Rain Check  but do not miss out!!!!
https://www.clipart.email/clipart/cartoon-clipart-group-presentation-397810.html

Tuesday, 14 April 2020

NORECOPA UPDATE

Hi there,
Norecopa, Norway's National Consensus Platform for the 3Rs,  has integrated the EU Commission Inventory of over 500 Education and Training Courses and other 3Rs-related resources into the Norecopa website. The searching of those resources is seamless and looks like this:
Why don't you try and get familiar with this search engine. It consolidates different sources and might save you valuable time!!!

Saturday, 29 February 2020

HPRA UPDATE FEB2020


...For lent we have another HPRA regulatory update. Please check your LAPBRU-USERS folder to get all the details or check your inbox with the circulated mail with the relevant attachemnt.
In summary....

  1. Without naming and shaming the HPRA has provided stats on non-compliance's trends and the most common causes. Live and learn!
  2. A reminder that the statistical returns are due has been included intros update given the time of the year.
  3. The National Committee has been quite proactive and has published guidelines for the named information officer and his/her training requirements. The NC is now busy organising a National 3R training event for the 17th of September. Keep the date free for networking and exchanging valuable practical information relevant to our roles.
  4. European Commission updates:
    1. Reports: 5-year report on implementing Dir 10/63/EU and Stast on animal use from 2015-2017.
    2. New ECVAM 3Rs resources to promote the uptake of alternatives and validation methods to in-vivo research.
  5. AWB Tasks:
    1. The HPRA has issued a reminder of the legal obligation of sharing tissues and of the existence of AniMatch
    2. The HPRA encourages proactive participation of the AWB in minimising severe suffering including a few suggestions on how.
  6. CULTURE OF CARE: Updates in Norecopa website, bench marking culture of care are the two main focus points included in this update.
  7. ANNEX III: The HPRA alerts and reminds researchers using farm animals of the importance to keep stocking densities compliant.
  8. ANIMAL STUDIES REGISTRIES: The HPRA strongly encourages that researchers register their studies in these registries outlining the aim of the study, the hypothesis, the experimental strategy and the analytical plans to avoid cherry-picking of findings and counter publication bias.
  9. CONTINUOUS TRAINING AND EDUCATION: the HPRA expects that each IA holder completes 8 hours/year, 40 hours in 5 years.
  10. NC3Rs: The link for updates is included as well as the use of tunnel for the handling of mice.
  11. USEFUL LINKS are also included, please check them put.

Sunday, 26 January 2020

APPLYING THE 3Rs: A CASE STUDY ON EVIDENCE AND PERCEPTIONS RELATING TO RAT CAGE HEIGHT IN THE UK

Please check this opinion paper at this link!
Animals 20199, 1104; doi:10.3390/ani9121104

Tuesday, 14 January 2020

LOOKING FOR SOMETHING TO READ?

Image result for update cartoon information"A flyer/poster was developed by NORECOPA to show its latest developments and it also gives useful links to the International Culture of Care Network, a compilation of severity classification systems for procedures and guidance documents for certain procedures such as toe-clipping and fasting in rodents:

The RSPCA has updated their website now including a new Reports and Resource hub. This now includes videos from a conference in Oxford on Animal Sentience:

Another Swedish study on group housing male mice was carried out by Swedish animal facilities:
https://www.mdpi.com/2076-2615/9/12/1010/htm

Regarding male mice, there is also another Nature publication out by Barabas et al, 2019, on ‘Proteome characterisation of used nesting material and potential protein sources from group housed male mice, ‘Mus musculus’:

The presentations from the Danish 3R-Centre Symposium, which took place in November 2019, are now available online, covering presentations like the mouse passport, the 9 to 5 rodent by Penny Hawkins, sex bias in pre-clinical research and handling and training for less stressed laboratory rodents (RISE Research Institute Sweden):

The RISE Research Institute Sweden has also made available a video in training and habituation techniques used for rodents at RISE:

Handling and training of rodents was also a topic of the 2019 NC3Rs/IAT Animal Technicians Symposium held in November 2019:

A new paper on ‘Confusing preclinical (predictive) drug screens with animal models of psychiatric disorders, or ‘disorder-like’ behaviour, is undermining confidence in behavioural neuroscience’:
Capas-Peneda et al (2019) from the University in Porto, Portugal, have developed a necropsy protocol for newborn mice: